Abstract #1640

MR angiography of congenital portosystemic shunts in mice

Hongxia Lei^1,2, Ana Francisca Soares³, and Rolf Gruetter^3,4

¹Animal Imaging and Technology CIBM-AIT, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ²University of Geneva, Geneva, Switzerland, ³Laboratory of functional and metabolic imaging LIFMET, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ⁴University of Lausanne, Lausanne, Switzerland

Abnormal vascular connections within the liver, such as congenital portosystemic shunts occur sporadically in widely used strain of laboratory mice, i.e. the C57BL/6J strain. We showed that with the respiration gating, MR angiography yields vascular structures of mouse liver with excellent quality and thus allowing diagnosing such abnormality non-invasively.

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