Abstract #1619

High-resolution 3D ultra-short echo-time imaging of the lung in young children at 3T without sedation

Wingchi Edmund Kwok^1,2, Clement Ren³, Gloria Pryhuber⁴, Mitchell Chess¹, and Jason C. Woods⁵

¹Department of Imaging Sciences, University of Rochester, Rochester, NY, United States, ²Rochester Center for Brain Imaging, University of Rochester, Rochester, NY, United States, ³Department of Pediatrics, University of Rochester, Rochester, NY, United States, ⁴Departments of Pediatrics and Environmental Medicine, University of Rochester, Rochester, NY, United States, ⁵Departments of Pediatrics and Radiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States

Our purpose was to study the feasibility of high-resolution lung ultra-short TE imaging of young children at 3T without sedation and tackle potential challenges. Two subjects aged 7 and 8 with mild cystic fibrosis were recruited. They were supported by a child life specialist and the use of a mock magnet. Siemens work-in-progress UTE and PETRA_D sequences were used for lung imaging. The images depicted the lung parenchyma, airways and vessels, and revealed abnormalities such as bronchial wall thickening. The techniques should be useful for the monitoring of lung development and evaluation of lung diseases in children.

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