Combined Intravoxel Incoherent Motion and Diffusion Tensor Imaging for Evaluation Renal Changes in Diabetic Nephropathy
Cheng long Wen1, Lihua Chen1, Fan Mao1, Yu Zhang2, and Wen Shen1
1Department of Radiology, Tianjin First Center Hospital, Tianjin, China, Tianjin, China, People's Republic of, 2Philips healthcare, Beijing, China., Beijing, China, People's Republic of
The
goal of this pilot study was to assess the ADC value in kidney of IVIM and DTI
in distinguishing diabetic subjects and healthy controls. In our study, cortical
ADC and D of patients with DN were significantly lower than those of healthy
controls. The reduction of D values in the cortex and medulla was more obvious than
ADC in patients. The results of this study suggested that
cortical D and ADC, quantified by kidney IVIM and DTI could be potential
imaging biomarkers for DN. IVIM could reflect the renal function more sensitive
and accurate in DN patients.
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