Toru Shirai1, Ryota Sato1, Yo Taniguchi1, Takenori Murase2, Atsushi Kuratani2, Taisei Ueda2, Takashi Tsuneki2, Yoshitaka Bito2, and Hisaaki Ochi1
1Research and Development Group, Hitachi, Ltd., Tokyo, Japan, 2Healthcare Campany, Hitachi, Ltd., Chiba, Japan
We have proposed that a
QSM reconstruction method combining an iterative least square minimization and adaptive edge-preserving filtering could
generate high-quality susceptibility maps. In this study, maps calculated by
the proposed method were compared qualitatively and quantitatively with those
calculated by COSMOS (a calculation of susceptibility
through multiple-orientation sampling) in healthy volunteers. The
results from human brain experiments showed good agreement with COSMOS. The
proposed QSM reconstruction of single orientation sampling is useful for generating a high-quality susceptibility
map of the human brain.