1Center for Neuroscience Imaging Research (CNIR), Institute for Basic Science (IBS), Suwon, Korea, Republic of, 2Department of Brain and Cognitive Engineering, Korea University, Seoul, Korea, Republic of, 3Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of
In chemical exchange
saturation transfer (CEST) MRI, multiple acquisition of imaging data with
varying saturation frequencies is typically performed, which prohibitively
prolongs imaging time. Furthermore, conventional, subtraction-based MTR
asymmetry analysis is prone to substantial errors, because the z-spectrum is
convoluted by CEST as well as inherent asymmetric MT, nuclear Overhauser
enhancement (NOE), etc. To tackle these problems, in this work we propose a
new, model-based direct Extraction of the z-spectrum Asymmetry from
undersampled k-space using SYmmetric basis (k-EASY) that incorporates main
field inhomogeneity correction and z-spectrum asymmetry analysis into a
framework of compressed sensing.
