1Translational Research Imaging Center, College of Medicine, Taipei Medical University, Taipei, Taiwan, 2Department of Radiology, School of Medicine, Taipei Medical University, Taipei, Taiwan, 3Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, 4Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan, 5Graduate Institute of Clinical Medicine, Taipei Medical University, Taipei, Taiwan