Hale Turnaoglu1, Kemal Murat Haberal1, Ozlem Isiksacan Ozen2, and Ahmet Muhtesem Agildere1
1Radiology, Baskent University, Faculty of Medicine, Ankara, Turkey, 2Pathology, Baskent University, Faculty of Medicine, Ankara, Turkey
Dialysis-related
amyloidosis that occurs secondarily to the deposition of amyloid fibrils containing
beta-2-microglobulin, is a type of amyloidosis affecting patients undergoing
long-term hemodialysis. It involves the osteoarticular system predominantly. Destructive
spondyloarthropathy, which frequently involves the
cervical spine, have
been reported only sporadically. CT is the best modality for detecting osseous
erosion or small
areas of osteolysis in
cortical bone. MRI shows the extent and distribution of
osseous, articular, spinal cord and soft-tissue involvement and indicates amyloid deposits in the
intervertebral disk,
synovium of apophyseal joints, and ligaments. The gold standart of the diagnosis is the histological identification of beta-2-microglobulin.
