Marcel Gutberlet1,2, Till Kaireit1,2, Andreas Voskrebenzev1,2, Julia Freise3, Tobias Welte3, Frank Wacker1,2, and Jens Vogel-Claussen1,2
1Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, 2Plattform Imaging, German Centre for Lung Research (DZL), Hannover, Germany, 3Clinic of Pneumology, Hannover Medical School, Hannover, Germany
Quantification
of regional lung ventilation is of high relevance for several lung diseases
like chronic obstructive lung disease (COPD) or asthma. In this study real-time
dynamic fluorinated gas MRI in free breathing for mapping of regional lung
ventilation was applied in patients with COPD and healthy volunteers. A
significant difference of washout kinetics between healthy volunteers and COPD
patients was found. Dynamic fluorinated gas MRI highly correlated with lung
function test which is used for COPD classification.
