Alex K. Smith1,2, Richard D. Dortch1,2,3, Samantha By1,2, Robert L. Barry2, Chris R. Thompson2, Kristen George-Durrett2, Bailey D. Lyttle2, and Seth A. Smith1,2,3
1Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, 2Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, 3Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States
The spinal
cord is responsible for mediating neurologic function, and in particular, the
lumbar cord is integral to lower extremity function. However, lumbar cord quantitative MRI studies
have been limited due to its size, location, and composition. A single-point quantitative magnetization
transfer was recently developed, but has not been applied to the lumbar
cord. Therefore, we have implemented an
assessment of qMT at the thoracolumbar bulge to characterize the MT effect in
the thoracolumbar cord in healthy volunteers.