NMR-based fecal metabolomics fingerprinting as predictors of earlier diagnosis in patients with colorectal cancer
Yan Lin1, Changchun Ma2, Zhening Wang1, Zhiwei Shen1, and Renhua Wu1
1Radiology Department, Second Affiliated Hospital, Shantou University Medical College, Shantou City, China, People's Republic of, 2Radiation Oncology, Cancer Hospital, Shantou University Medical College, Shantou City, China, People's Republic of
Colorectal cancer (CRC) is a growing
cause of mortality in developing countries, warranting investigation into its
earlier detection for optimal disease management.This study aimed to validate the
ability of NMR-based fecal metabolomics fingerprinting as predictors
of earlier diagnosis in CRC patients.Our findings revealed that the fecal metabolic
profiles of healthy controls can be distinguished from CRC patients, even in
the early stage (stage I/II), highlighting the potential utility of NMR-based
fecal metabolomics fingerprinting as predictors of earlier diagnosis in CRC patients.
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