Abstract #0819

Non-invasive cardiac stimulation with MR guided HIFU: a rapid, cardiac triggered, MR-ARFI method for direct visualization of stimulation site and assessment of tissue stiffness.

Pierre Bour^1,2, Fabrice Marquet², Fanny Vaillant², Valery Ozenne², Solenn Toupin^2,3, Matthieu Lepetit coiffe³, Erik Dumont¹, and Bruno Quesson²

¹IGT, PESSAC, France, ²IHU-LIRYC, PESSAC, France, ³Siemens Healthcare, Saint-Denis, France

HIFU cardiac stimulation may enable diagnostic and therapeutic applications such as noninvasive electrophysiological exam, emergency care and temporary stimulation. In-vivo proof of concept of HIFU cardiac stimulation has already been done on pig. We propose here a first proof of feasibility to monitor the displacement induced by acoustic radiation force impulse (MR-ARFI) during contactless stimulation ex-vivo, on a beating pig heart model. ARFI displacement maps will be used for precise localization of the depolarization source and a quantification of displacement will be done during refractory (contraction) and non-refractory (resting time) period.

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