Abstract #0798

Free-breathing Diffusion Tensor Imaging of the In Vivo Human Heart - Stimulated Echo vs. Spin Echo Acquisition

Constantin von Deuster^1,2, Christian T. Stoeck^1,2, Martin Genet², David Atkinson³, and Sebastian Kozerke^1,2

¹Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom, ²Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, ³Centre for Medical Imaging, University College London, London, United Kingdom

In vivo cardiac Diffusion Tensor Imaging (DTI) using the Stimulated Echo Acquisition Mode (STEAM) is particularly challenging during free breathing acquisition. To address this limitation, spin echo (SE) sequences employing motion-compensated diffusion gradients may be used. In this work, scan time, SNR efficiency and diffusion tensor metrics are compared between the STEAM method and a second-order motion compensated SE approach. For SE, SNR and gating efficiency were increased by 2.65 and 29% relative to STEAM, respectively. It is concluded that the SE method is an attractive alternative to STEAM based approaches for in vivo free-breathing cardiac DTI.

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