Simultaneous electrical stimulation of DBS electrodes and fMRI in movement disorders.
Stephen Edward Jones1, Hyun-Joo Park2, Pallab Bhattacharyya1, and Andre Machado2
1Imaging Institute, Cleveland Clinic, Cleveland, OH, United States, 2Neurologic Institute, Cleveland Clinic, Cleveland, OH, United States
We present a new intra-operative MRI technique for evaluating placement of DBS electrodes in patients with movement disorders, using simultaneous electrical stimulation and fMRI. This technique can elicit a strong BOLD effect whose pattern can reflect underlying networks. There is strong spatial sensitivity of these patterns to electrode position, which is important for clinical utility in predicting clinical response and unwanted side-effects.
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