Yosuke Ishii1,2, Tadashi Nariai1, Yoji Tanaka1, HIroshi Aihara2, Yoshio Suyama2, Shinichi Wakabayashi2, and Taketoshi Maehara1
1Neurosurgery, Tokyo Medial and Dental University, Tokyo, Japan, 2Neurosurgery, Suiseikai Kajikawa Hospital, Hiroshima, Japan
We used dynamic susceptibility contrast (DSC)-MRI to evaluate the chronological
changes in hemodynamics after indirect bypass surgery for moyamoya
disease. Twenty five patients who underwent indirect bypass surgery and repeated DSC–MRI measurement within the first 6 postoperative
months were included. We analyzed mean transit time (MTT) delay using the
cerebellum as control. Mean MTT delay in the anterior circulation area
gradually decreased soon after surgery and stabilized after 3 postoperative
months. Postoperative MTT delay values were significantly decreased
compared with preoperative values from 1 to 2 weeks onwards. These results
suggested DSC–MRI detected angiogenesis during the early postoperative stages.
