1Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 2Shengjing Hospital of China Medical University, Shenyang, China, People's Republic of, 3Philips Healthcare, Beijing, China, People's Republic of
Knowledge of CBF in neonates or infants may provide valuable information
in many pathological conditions. When applied to very young children, CBF
mapping using arterial-spin-labeling (ASL) MRI suffers from low SNR and poor
quantification, whereas phase-contrast (PC) MRI may provide reliable estimation
of global CBF. Therefore, this study aim to 1) provide a set of age-specific PC-MRI
protocols for CBF quantification in children under 1.5 years old; 2) establish
typical arterial flow velocity in children at this age which could guide future
ASL efforts in labeling pulse optimization; 3) report how CBF changes during this
early stage of life.
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