Wendy Ni1,2, Thomas Christen2, and Greg Zaharchuk2
1Department of Electrical Engineering, Stanford University, Stanford, CA, United States, 2Department of Radiology, Stanford University, Stanford, CA, United States
Transverse MR spin relaxation rates, R2*, R2 and
R2’ have all been considered sensitive to brain tissue oxygenation. In this study, we focus on a cohort of
pre-operative Moyamoya disease patients and simultaneously map all three rates
in addition to cerebral blood flow, both before and after the injection of the
vasodilatory drug, acetazolamide. We
found our measurements to be consistent with physiology and previous studies,
and to support the use of R2’ for oxygenation mapping instead of R2* and R2.
