Diana Khabipova1,2, Rita Gil2, Marcel Zwiers2, and José Pedro Marques2
1CIBM-AIT, EPFL, Lausanne, Switzerland, 2Centre for Cognitive Neuroimaging, Donders Institute, Nijmegen, Netherlands
Anisotropic microstructure of
the white matter causes the apparent transverse relaxivity, $$$R_2^*$$$, to
depend on the orientation of white matter fibres in respect to the applied
magnetic field. Using the fibre orientation prior knowledge from DTI
orientation dependent $$$R_{2,ANISO}^*$$$ and independent $$$R_{2,ISO}^*$$$ components of $$$R_2^*$$$ were
calculated. For all studied WM fibres a consistency for the
(an)isotropic components between both hemispheres was present. The isotropic
component showed higher variability compared to the anisotropic component.
