Optimized Inversion-Time Schedules For High-Resolution Multi-Inversion EPI Quantitative Measurements of T1
Ouri Cohen1,2, Ville Renvall3, and Jonathan Polimeni1,2
1Athinoula A. Martinos Center, Charlestown, MA, United States, 2Radiology, Massachusetts General Hospital, Boston, MA, United States, 3Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland
A novel optimized method for high-resolution quantitative EPI measurements of T1 is introduced and validated on a 3T clinical scanner in a phantom and a healthy volunteer. The method offers a 5-fold acceleration in scan time over previous techniques allowing fully quantitative 1.2 mm3 isotropic T1 maps in less than 30 seconds.
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