Conjoint measure of 3D ASL and 3D APT in the lesion proximal regions for differentiating metastasis tumor from glioblastom
Rui Li1, Bing Wu2, Chien-yuan Lin3, Xin Lou1, YuLin Wang1, and Lin Ma1
1Department of Radiology, PLA general Hospital, Beijing, China, People's Republic of, 2GE healthcare MR Research China, Beijing, China, People's Republic of, 3GE heathcare Taiwan, Taipei, Taiwan
Differential diagnosis is challenging due to similar appearance using conventional imaging such as T1 contrast enhanced and DWI. In this work, we use the measure of spatially matching 3D arterial
spin labeling (ASL) and 3D amide proton transfer (APT) in the lesion proximal
regions to differentiate metastasis and glioblastom, in the hypothesis that glioblastom
infiltrates into sourrounding tissues whereas metastasis tumors have clear biological boundaries.
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