Abstract #0268

Noninvasive Measurement of Single Renal Oxygen Extraction Fraction using Focused Asymmetric Spin Echo Approach - a feasibility study

CY Wang¹, R Zhang², L Jiang³, R Wang⁴, XD Zhang⁴, H Wang³, K Zhao⁴, LX Jin³, J Zhang^1,2, XY Wang^1,4, and J Fang^1,2

¹Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China, People's Republic of, ²College of Engineering, Peking University, Beijing, China, People's Republic of, ³Philips Healthcare, Suzhou, China, People's Republic of, ⁴Department of Radiology, Peking University First Hospital, Beijing, China, People's Republic of

This study demonstrates the feasibility of combining 2D-RF excitation pulse and ASE sequence (focused ASE sequence, FASE) for single renal OEF measurement. Comparison between images acquired with full-FOV ASE and focused ASE was conducted to confirm the advantages of the focused ASE sequence for single renal imaging. The new technique could reduce artifacts and distortion caused by susceptibility differences, and limit spatial blurring due to T2-decay, which is promising for diagnosis of some renal diseases.

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