Abstract #0199

Time-resolved 23-Na Imaging for Monitoring of Thermochemical Ablation Injections

Nicolas G.R. Behl¹, Armin M. Nagel^1,2, Erik N.K. Cressman³, Reiner Umathum¹, David Fuentes⁴, R. Jason Stafford⁴, Peter Bachert¹, Mark E. Ladd¹, and Florian Maier¹

¹Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Diagnostic and Interventional Radiology, University Medical Center Ulm, Ulm, Germany, ³Interventional Radiology, M. D. Anderson Cancer Center, Houston, TX, United States, ⁴Imaging Physics, M. D. Anderson Cancer Center, Houston, TX, United States

Thermochemical ablation (TCA) is a novel minimally invasive ablation approach. Acetic acid and sodium hydroxide are injected simultaneously and mix and react directly before entering the tissue. The exothermal reaction releases heat that is used for thermal ablation. For a detailed characterization of TCA injection, 4D ²³Na-data with reasonable temporal resolution are required. In this work, a compressed sensing approach was applied to acquire 4D ²³Na-data of injections with high spatial and good temporal resolution.

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