Quantitative Liver Function Analysis using Volumetric T1 Mapping with Fast Multi-Slice B1 Correction on Hepatocyte-specific Contrast Enhanced Liver Magnetic Resonance Imaging
Jeong Hee Yoon1, Jeong Min Lee1, Eun Ju Kim2, Tomoyuki Okuaki3, and Joon Koo Han1
1Radiology, Seoul National University Hospital, Seoul, Korea, Republic of, 2Philips Healthcare, Seoul, Korea, Republic of, 3Philips Healthcare, Tokyo, Japan
Liver signal intensity on hepatobiliary phase at
gadoxetic acid-enhanced liver MRI has been reported to be useful to estimate
global and regional liver function quantitatively. However, simple MR signal
measurement is often suffering from its sensitivity of MR field inhomogeneity
and non-linear relationship with contrast medium concentration. Herein, we investigated
of B1 correction effect on T1 map and compared its diagnostic performance to
assess liver function according to Child-Pugh classification. In addition, we
attempted to investigate risk assessment capability of B1 corrected T1 map for long-term
clinical outcome in patients with cirrhosis.
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