Role of the Intravoxel Incoherent Motion (IVIM) Imaging in the Pre-treatment Prediction and Early Response Monitoring for Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
1department of radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China, People's Republic of, 2GE Healthcare MR Research China, Beijing, China, People's Republic of
Purpose: to
explore whether IVIM can determine pre-treatment
differences or monitor early response in breast cancer patients receiving NAC.
Materials and Methods: thirty-six
patients examined with multiple-b DWI were divided into MHR and NMHR groups. Parameters
between MHR
and NMHR
groups were compared.
Results: the
D and f value at the baseline and mid-treatment of NAC showed significantly differences
between MHR and NMHR.
△D and △f were significantly higher in MHR than in
NMHR.
Conclusion: the
D and f value showed potential value in the pre-treatment prediction and early
response monitoring to NAC in local advanced breast.
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