Abstract #0117

U-fiber Quantification in Non-Lesional Epilepsy

Rafael O'Halloran¹, Rebecca Feldman¹, Madeline Fields¹, Laura Marcuse¹, and Priti Balchandani¹

¹Icahn School of Medicine at Mount Sinai, New York, NY, United States

A method for the quantification of cortical-to-cortical U-fiber fraction based on 7T MRI is presented and used to demonstrate group differences in the the U-fiber fractions in non-lesional and lesional epilepsy patients compared to healthy controls. Non-lesional epilepsy patients had the lowest u-fiber fractions followed by healthy control subjects, and then by lesional epilepsy subjects with the highest u-fiber fractions.

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