Longitudinal Evaluation of Cartilage Component of Matrix-Associated Autologous Chondrocyte Transplants using Biochemical MR Imaging
Xian Xu1, Ningyu An1, Panli Zuo2, and Esther Raithel3
1Department of Radiology, Chinese PLA General Hospital, Beijing, China, People's Republic of, 2Siemens Healthcare, MR Collaborations NE Asia, Beijing, China, People's Republic of, 3Siemens Healthcare GmbH, Berlin, Germany
This
study combined T2 mapping and delayed gadolinium-enhanced MRI of cartilage
(dGEMRIC) technique to evaluate the repair cartilage tissue after
Matrix-associated autologous chondrocyte implantation (MACI). We found that the
T2 and ΔR1 values of the repair tissue were significantly higher than the
native tissue at 1, 3 and 6 months after MACI, but showed a downward trend and
showed no difference with native tissue at 12 months, which suggested that
the integrity of the collagen and GAG of repair tissue was similar to native
cartilage.
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