Abstract #4795
High Resolution Double Resonant 1 H/ 19 F RF Coil for Small Rodent MRI and MRS at 3T
Helmar Waiczies 1 , Jan Rieger 1 , Andreas Graessl 2 , Andreas Pohlmann 2 , Matthias A. Dieringer 2,3 , and Thoralf Niendorf 2
1
MRI.TOOLS GmbH, Berlin, Germany,
2
Berlin
Ultrahigh Field Facility (B.U.F.F.), Max Delbrck Center
for Molecular Medicine, Berlin, Germany,
3
3Working
Group on Cardiovascular Magnetic Resonance, Experimental
and Clinical Research Center (ECRC), Berlin, Germany
A dual-tuned
1
H/
19
F
birdcage coil with high B
1
+
homogeneity
for animal research at a clinical 3T-System has been
constructed. The simulated B
1
+
fields
and the measured B
1
+
maps
were found to be in good agreement, including anatomical
coverage, B
1
+
distribution
and B
1
+
efficiency.
The acquired ex vivo images showed superb sensitivity
for
19
F
MRI as well as high spatial resolution for
1
H
MRI. This work demonstrates the feasibility of a double
tuned birdcage coil tailored for
1
H/
19
F
MR in small rodents using a clinical 3T MR system. The
proposed RF coil provides high homogeneity and
sensitivity for very low concentrations of
19
F.
This progress may serve to enhance the capabilities of
19
F
MR based cell tracking in small rodents and benefits
translational research en route to
19
F
MR in large animals or even humans.
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