Abstract #4782
The application of functional challenge tasks in Moyamoya patients
Chou-Ming Cheng 1,2 , Jin-Jie Hung 1 , Hsiao-Wen Chung 3 , Hung Sheng Che 4 , Muh-Lii Liang 5 , Jen-Chuen Hsieh 1 , Shing-Jong Lin 1 , and Tzu-Chen Yeh 4
1
Department of Medical Research and
Education, Taipei Veterans General Hospital, Taipei,
Taiwan, Taiwan,
2
Graduate
Institute of Biomedical Electronics and Bioinformatics,
National Taiwan University, Taipei, Taiwan, Syrian Arab
Republic,
3
Graduate
Institute of Biomedical Electronics and Bioinformatics,
National Taiwan University, Taipei, Taiwan, Taiwan,
4
Department
of Radiology, Taipei Veterans General Hospital, Taipei,
Taiwan, Taiwan,
5
Neurosurgery
Neurological Institute, Taipei Veterans General
Hospital, Taipei, Taiwan, Taiwan
Moyamoya disease is characterized by Moyamoya vessels
near the stenosis regions induced by progressive
stenosis of the internal carotid artery, cerebral
artery. CVR and OEF are critical indicators of the
severity in Moyamoya disease. In this research, blood
oxygenation level dependence (BOLD) functional Magnetic
Resonance Imaging (fMRI) of carbogen inhalation and hand
grasping are adapted as challenge tasks to probe CVR and
OEF in Moyamoya disease.
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