Abstract #4748
Quantitative Carotid MR/PET Imaging: Comparisons to PET/CT and clinical evaluation of MR-Attenuation Correction versus CT-Attenuation Correction in MR/PET Emission Data
Jason Bini 1,2 , Philip M Robson 1 , Claudia Calcagno 1 , Mootaz Eldib 1 , and Zahi A Fayad 1
1
Translational and Molecular Imaging
Institute, Icahn School of Medicine at Mount Sinai, New
York, New York, United States,
2
Department
of Biomedical Engineering, The City College of New York,
New York, New York, United States
18F-Fluorodeoxyglocuse (FDG) positron emission
tomography (PET) has shown promise in quantifying
metabolic activity of inflammation in atherosclerotic
plaques in patients. In this study, we examine the
quantitative differences between our carotid artery
imaging protocol on a PET/CT and an MR/PET scanner,
controlling for circulation time. Large differences
between PET/CT and MR/PET were observed. When
reconstructing the same PET data with MR- and CT-based
attenuation maps in the MR/PET reconstruction we see a
high quantitative correlation between reconstructed PET
images. This study supports the use of MR/PET for
quantitative measure of metabolic activity in the
carotid arteries.
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