Meeting Banner
Abstract #4648

Gender-Specific Templates of T1, T2 and mcDESPOT Myelin Water Fraction Map Spanning Early Childhood

Sean Deoni 1 , Jonathan O'Muircheartaigh 2 , Holly Dirks 1 , Nicole Waskiewicz 1 , Lindsay Walker 1 , and Douglas Dean 1

1 Advanced Baby Imaging Lab, Brown University, Providence, Rhode Island, United States, 2 Neuroimaging, King's College London, England, United Kingdom

Few studies to-date have aimed to comprehensively investigate or map early infant brain development, despite this period being a crucial period of brain and behavioral maturation. In this work, we used the mcDESPOT relaxometry method to quantitative evaluate T1, T2 and myelin water fraction, VFM, in a large sample of healthy and typically-developing children 2.5 months to 5.5 years of age. From 424 total datasets, 14 mean male and female T1, T2 and VFM maps were created spanning 3 to 60 months of age. These publicly-available data ( provide an unprecedented view into normal brain development.

This abstract and the presentation materials are available to members only; a login is required.

Join Here