Meeting Banner
Abstract #4641

Investigation of normal brain aging in rodent experimental model by DTI, Volumetry and localized proton spectroscopy

Stefano Tambalo 1 , Alessandro Daducci 2 , Elisa Mosconi 1 , Silvia Fiorini 1 , Nicolo' Sonato 1 , Marta Balietti 3 , Patrizia Fattoretti 3 , Andrea Sbarbati 4 , and Pasquina Marzola 5

1 Dept. of Neuological and Movement Science, Universit di Verona, Verona, Verona, Italy, 2 STI IEL LTS5, EPFL, Lausanne, Switzerland, 3 Neurobiology of Aging Laboratory and Cellular Bioenergetics Laboratory, I.N.R.C.A. (Italian National Centres on Aging), Ancona, Italy, 4 Dept. of Neuological and Movement Science, INSTM Firenze, Verona, Italy, 5 Dept. of Computer Science, University of Verona, Verona, Italy

In the last decade many studies of human brain aging based on MRI advanced techniques have been published. Clinical studies are potentially affected by several factors, such as life-style or genetic variability. Experimental models of aging could be useful in dissecting physiological from pathophysiological events as well as the impact of environmental or genetic factors. They could also represent a platform to study the effect of pharmacological and non-pharmacological therapies in delaying brain aging. Aim of present work was the investigation of brain aging in a rodent experimental model by advanced MRI techniques and the assessment of its potential translational value.

This abstract and the presentation materials are available to members only; a login is required.

Join Here