Abstract #4620
Abnormal cortical and thalamic development in children with Borderline Intellectual Functioning
Niels Bergsland 1,2 , Francesca Baglio 1 , Gisella Baglio 1 , Raffaello Nemni 1,3 , Mario Clerici 1,3 , Michela Zanette 1 , and Valeria Blasi 1
1
Istituto IRCCS Santa Maria Nascente,
Fondazione Don Gnocchi, Milan, Italy,
2
Dipartimento
di Elettronica, Informatica e Bioingegneria, Politecnico
di Milano, Milan, Italy,
3
Universit
degli Studi di Milano, Milan, Italy
Borderline Intellectual Functioning (BIF) children
present with cognitive, motor, social and adaptive
limitations that result in learning disabilities and are
more likely to develop psychiatric disorders later in
life. It has become increasingly recognized that gray
matter plays a significant role in this condition. The
current study compared BIF and typically developing
groups of children in measures of cortical
thickness/area as well as subcortical structural volumes
in BIF. It was shown that BIF children present with
brain development delay in cortical areas and that
thalamus which are associated with motor and cognitive
abilities crucial for intellectual functioning.
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