Abstract #4560
Accelerated In Vivo 3D Pseudo-Continuous ASL with Balanced Steady State Free Precession using k-t FOCUSS
Paul Kyu Han 1 , Jong Chul Ye 1 , Seung Hong Choi 2 , and Sung-Hong Park 1
1
Department of Bio and Brain Engineering,
Korea Advanced Institute of Science and Technology,
Daejeon, Korea,
2
Department
of Radiology, Seoul National University College of
Medicine, Seoul, Korea
pCASL is a non-invasive technique that measures blood
perfusion. Recently, pCASL with bSSFP has been proposed
to overcome the limitations of EPI, however, the low
temporal resolution may lead to limited spatial
coverage. One potential approach to improve the spatial
coverage of pCASL-bSSFP is to use compressed sensing
(CS). We implemented the first accelerated in-vivo
imaging of 3D pCASL-bSSFP with k-t FOCUSS at 3T for
human brain. Experimental results show that CS
acceleration by a factor of 4 works well for pCASL-bSSFP,
which confirms that combination of CS and pCASL-bSSFP
may be a good solution for distortion-free blood
perfusion imaging.
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