Abstract #4493
A Combined Analysis of the Non-Gaussian Diffusion Methods in Monte Carlo Simulations, Anisotropic Fibre Phantoms, and in in vivo Human Brain Tissues
Farida A Grinberg 1 , Ezequiel Farrher 1 , Ivan I Maximov 1 , and N. Jon Shah 1,2
1
INM-4, Forschungszentrum Juelich, Juelich,
Germany,
2
Department
of Neurology, RWTH Aachen University, Aachen, Germany
This work provides a comparative analysis of the four
non-monoexponential functions in fitting the diffusion
response in a) the Monte Carlo diffusion simulations in
a set of cylindrical objects, b) synthetic fibre
phantoms with parallel and crossing fibres, and c) in
vivo human brain tissue. All functions including the
diffusion kurtosis, stretched-exponential, the
lognormal- and gamma-distribution functions were shown
to provide complimentary information and different
contrasts in parameter maps.
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