Abstract #4486
Two-component Low Q-space Diffusion MRI in Evaluation of Spinal Cord in Patients with Cervical Spondylosis in Vivo: a Feasibility Study
Masaaki Hori 1 , Koji Kamagata 1 , Mariko Yoshida 1 , Nozomi Hamasaki 2 , Shuji Sato 2 , Kouhei Kamiya 1,3 , Yuriko Suzuki 4 , Michimasa Suzuki 1 , and Shigeki Aoki 1
1
Radiology, Juntendo University School of
Medicine, Tokyo, Japan,
2
Juntendo
University Hospital, Tokyo, Japan,
3
Radiology,
The University of Tokyo, Tokyo, Japan,
4
Philips
Electronics Japan, Ltd, Tokyo, Japan
We investigate two-component low q-space diffusion MRI
in evaluation of microstructural changes in the spinal
cord in patients with cervical spondylosis in vivo, as a
feasibility study. Five patients were enrolled in this
study. There were significant differences in root mean
square displacement of water molecules in extra- and
intra- cellular spaces between compressed and
uncompressed area in the spinal cords. More studies of
the imaging pathological correlation and improvement of
image quality are needed; this technique has the
potential to provide new information in patients with
spinal cord in vivo.
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