Abstract #4461
Correction of Off-resonance Distortions in In-vivo Cardiac Diffusion Tensor Imaging
Jack Harmer 1 , Rachel W Chan 2 , Christian T Stoeck 3 , Constantin V Deuster 3 , David Atkinson 2 , and Sebastian Kozerke 1,3
1
Division of Imaging Sciences & Biomedical
Engineering, King's College London, London, United
Kingdom,
2
Centre
for Medical Imaging, University College London, London,
Greater London, United Kingdom,
3
Institute
for Biomedical Engineering, University and ETH Zurich,
Zurich, Switzerland
Advances in diffusion acquisition schemes employing
stimulated echo modes now allow diffusion tensor imaging
of the beating heart. However these pulse sequences
almost invariably use single shot EPI readout modules
that are extremely sensitive to magnetic field
inhomogeneities. We demonstrate the feasibility of
acquiring fully sampled single-shot in-vivo cardiac DTI
data at 3T, in order to maximise SNR, by employing
off-resonance correction as part of the reconstruction
process. We demonstrate that such correction can be used
to accurately reconstruct the correct geometry in areas
of severe geometric distortion and signal pileup, whilst
still allowing diffusion tensors to be reconstructed.
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