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Abstract #4409

Optimal reconstruction using receive arrays for hyperpolarized 13 C cardiac imaging at 3T

William Dominguez-Viqueira 1 , Angus Z Lau 2 , Albert P Chen 3 , and Charles H Cunningham 1,4

1 Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada, 2 University of Oxford, United Kingdom, 3 GE healthcare, Toronto, Ontario, Canada, 4 Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

Rapid multislice imaging of hyperpolarized 13C pyruvate was demonstrated by using a single-shot spiral pulse-sequence with up to 5-channel receiver-coils. SNR and coverage can be increased by using multi-channel reception as presented before; but final images are biased by the coil sensitivity when a simple sum-of-squares channel combination was used. In this work coil sensitivity coefficients were numerically calculated in Matlab and used for optimal linear combination reconstruction with in vivo measurements. SNR improvements of up to a 100 % in areas closer to the base of the heart were demonstrated by using the optimal reconstruction, as compared with sum-of-squares.

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