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Abstract #4363

Fast, Free-breathing 3D T2 mapping at 3T in 5 min for Whole-Heart Myocardial BOLD MRI

Hsin-Jung yang 1 , Jianing Pang 1 , Behzad Sharif 1 , Avinash Kali 1 , Xiaoming Bi 2 , Ivan Cokic 1 , Diabao Li 1 , and Rohan Dharmakumar 1

1 Cedars Sinai Medical Center, Los Angeles, California, United States, 2 Siemens Medical Solutions, IL, United States

Myocardial BOLD CMR is an appealing alternative to contrast-enhanced methods for the functional assessment of coronary artery disease. While significant advances have been made in BOLD CMR, limitations still exist. An ideal BOLD CMR method would be able to overcome the limitations by permitting acquisition of 3D myocardial BOLD images as maps (T2 or T2*) within 5 minutes, without the need to suspend breathing. In this work, we developed a stack-of-stars k-space acquisition scheme, which permits 100% acquisition efficiency, to construct 3D T2 maps with full LV coverage within 5 minutes. We tested this approach in healthy human volunteers.

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