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Abstract #4357

Improved Spiral first-pass perfusion imaging with Motion-Corrected Compressed Sensing

Yang Yang 1 , Craig H Meyer 1,2 , Christopher M Kramer 2,3 , and Michael Salerno 2,3

1 Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 2 Radiology, University of Virginia, Charlottesville, VA, United States, 3 Medcine, University of Virginia, Charlottesville, VA, United States

Compressed sensing (CS) has shown promise for highly accelerated first-pass perfusion imaging. However CS techniques suffer from temporal blurring in the presence of respiratory motion which is inevitable in clinical breath-held perfusion scans. Spiral pulse sequences have multiple advantages for myocardial perfusion imaging and their relatively incoherent aliasing pattern is advantageous for CS reconstruction. We have developed a parallel imaging and CS reconstruction technique for spiral first-pass perfusion imaging which incorporates a registration operator directly into the reconstruction model and thus outputs a series of motion-free perfusion images. We demonstrate high image quality and robustness to respiratory motion.

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