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Abstract #4349

A new, highly effective slicewise motion correction for BOLD MRI: SLOMOCO

Erik Beall 1 and Mark Lowe 1

1 Imaging Institute, Cleveland Clinic, Cleveland, OH, United States

Head motion artifact is a major unsolved problem for fMRI and fcMRI. The primary reason why current methods do not solve motion is the limitation of volume-synchronized or -interpolated motion. Real motion happens at the slice level, and this has been shown to seriously limit accuracy of volumetric measures. Improved correction requires knowledge of slice-level motion, and in a major advance for the field, we present an algorithm that obtains this. Using a motion-injection sequence to acquire realistic motion-corrupted data in cadavers, we show the algorithm obtains the known motion parameters with accuracy on the level of external trackers.

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