Abstract #4319
Comparison of accelerated T1-weighted whole-brain structural imaging protocols
Pavel Falkovskiy 1,2 , Daniel Brenner 3 , Thorsten Feiweier 4 , Stephan Kannengiesser 4 , Bndicte Marchal 1,2 , Tobias Kober 1,2 , Alexis Roche 1,5 , Kaely Thostenson 6 , Denise Reyes 6 , Matthias Seeger 7 , Tony Stoecker 3 , Matt Bernstein 6 , and Gunnar Krueger 1,2
1
Advanced Clinical Imaging Technology,
Siemens Healthcare IM BM PI, Lausanne, Switzerland,
2
CIBM
- AIT, cole Polytechnique Fdrale de Lausanne,
Lausanne, Switzerland,
3
German
Center for Neurodegenerative Diseases (DZNE), Bonn,
Germany,
4
Healthcare
Sector, Siemens AG, Erlangen, Germany,
5
Department
of Radiology, University Hospital (CHUV), Lausanne,
Switzerland,
6
Department
of Radiology, Mayo Clinic, Rochester, Minnesota, United
States,
7
Laboratory
for Probabilistic Machine Learning, cole Polytechnique
Fdrale de Lausanne, Lausanne, Switzerland
The MPRAGE pulse sequence is often used for structural
brain imaging because of its good GM/WM contrast.
Recently, several strategies beyond conventional
parallel imaging have been proposed that can be applied
to further shorten the several-minute-long 3D whole
brain acquisition time, e.g. 2D-GRAPPA, CAIPIRINHA, and
segmented MPRAGE. This work qualitatively and
quantitatively compares the performance of four 3-minute
MPRAGE variants of the frequently employed 5-minute
ADNI-2 3D brain imaging protocol. All images obtained
with a 3-minute protocol are rated as being of
clinically useful image quality, though the fast
protocols are found to introduce systematic deviations
in automated volumetric measurements.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
