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Abstract #4307

An Automatic Guinea Pig Brain Extraction Method

Jiehua Li 1 , Jason M Zara 1 , Rao P Gullapalli 2 , and Jiachen Zhuo 2

1 Electrical and Computer Engineering, George Washington University, Washington, District of Columbia, United States, 2 Diagnostic Radiology and Nuclear Medicine, Universit of Maryland School of Medicine, Baltimore, Maryland, United States

There has been growing number of MRI studies using guinea pigs as animal models, however there has been no automatic brain extraction algorithm available for guinea pig brain extraction. In this study, we describe a guinea pig brain deformable model method (GBD) based on our previous rat brain extraction method (RBD). GBD is a template-based approach with adjusted model parameters compared to RBD. We validated GBD on 20 guinea pig T2-weighted images and achieved an extraction accuracy of above 90%.

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