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Abstract #4300

Attenuation correction for PET/MR using continuous pseudo-CT derived from MR T1w and population CT images

Yasheng Chen 1 , Meher Juttukonda 1 , Yi Su 2 , Tammie Benzinger 2 , Brian Rubin 3 , Yueh Z Lee 1 , Felipe Espinoza 4 , Weili Lin 1 , Dinggang Shen 1 , David S Lalush 5 , and Hongyu An 1

1 Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States, 2 Radiology, Washington University in St. Louis, St. Louis, MO, United States, 3 Surgery and Radiology, Washington University in St. Louis, St. Louis, MO, United States, 4 Radiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States, 5 Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

An atlas based method has been developed to derive pseudo continuous CT images using MR T1w images for PET attenuation correction. Population probabilistic map for air space segmentation and a sparse regression to enhance the local structure similarity were employed to achieve an improved AC accuracy.

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