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Abstract #4280

Three Dimensional Quantitative Myelin Water Imaging using Direct Visualization of Short Transverse Relaxation Time Component (ViSTa)

Se-Hong Oh 1,2 , Sung Suk Oh 2 , Joon Yul Choi 2 , Jang-Yeon Park 3 , and Jongho Lee 2

1 Imaging Institute, Cleveland Clinic, Cleveland, Ohio, United States, 2 Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States, 3 School of Biomedical Engineering, College of Biomedical and Health Science, Konkuk University, Chungju, Korea

In this study, a new 3D myelin water imaging sequence that covers the entire brain (FOV = 240 240 128 mm^3; resolution = 1.5 1.5 4 mm^3) in less than 8 minutes was developed. This method is based on a recently proposed novel approach to MWI, called Direct Visualization of Short Transverse Relaxation Time Component (ViSTa). It provides a high quality myelin water fraction map.

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