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Abstract #4225

3D Compressed Sensing CPMG with Group-Sparse Reconstruction for Myelin Water Imaging

Henry Szu-Meng Chen 1,2 , Angshul Majundar 3 , and Piotr Kozlowski 4

1 UBC MRI Research Centre, Vancouver, British Columbia, Canada, 2 Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, 3 Indraprastha Institute of Informatino Technology, New Delha, DL, India, 4 Radiology, University of British Columbia, Vancouver, BC, Canada

Myelin water imaging using CPMG sequence is slow, which is especially a concern in in vivo cases. Compressed sensing 3D CPMG experiments were performed on ex vivo cervical spinal cord sample using a variable density sampling scheme in the two phase encode directions. It was found that while the T2 weighted echo images were accurately reconstructed at 3x and 2x acceleration, the 3x accelerated myelin water fraction maps showed higher reading than the fully sampled reference dataset. The 2x accelerated scan did not have this issue.

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