Abstract #4225
3D Compressed Sensing CPMG with Group-Sparse Reconstruction for Myelin Water Imaging
Henry Szu-Meng Chen 1,2 , Angshul Majundar 3 , and Piotr Kozlowski 4
1
UBC MRI Research Centre, Vancouver, British
Columbia, Canada,
2
Physics
and Astronomy, University of British Columbia,
Vancouver, BC, Canada,
3
Indraprastha Institute
of Informatino Technology, New Delha, DL, India,
4
Radiology,
University of British Columbia, Vancouver, BC, Canada
Myelin water imaging using CPMG sequence is slow, which
is especially a concern in
in
vivo
cases.
Compressed sensing 3D CPMG experiments were performed on
ex
vivo
cervical
spinal cord sample using a variable density sampling
scheme in the two phase encode directions. It was found
that while the T2 weighted echo images were accurately
reconstructed at 3x and 2x acceleration, the 3x
accelerated myelin water fraction maps showed higher
reading than the fully sampled reference dataset. The 2x
accelerated scan did not have this issue.
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