Meeting Banner
Abstract #4206

The End-Tidal CO2 Response Function in Resting-State BOLD fMRI

Ali M Golestani 1,2 and J Jean Chen 1,2

1 Rotman Research Institute, Baycrest, Toronto, ON, Canada, 2 University of Toronto, Toronto, ON, Canada

End-tidal CO2 (PETCO2) fluctuations constitute a source of physiological noise in the BOLD fMRI signal. In this study we estimate the hemodynamic response of the resting-state BOLD signal to spontaneous PETCO2 fluctuations. Cardiac, respiratory and PETCO2 signals were recorded during resting-state fMRI scan. The response is estimated voxel-wise in 8 subjects. The estimated PETCO2 response has a peak around 9 seconds, which is in accordance with previously reported results. There is some overlap between the regions most affected by RVT and by PETCO2 fluctuations showing possible interaction between the two, but they each modulates the BOLD signal in unique ways.

This abstract and the presentation materials are available to members only; a login is required.

Join Here