Abstract #4192
Modulation of Resting State Functional Connectivity of the Motor Network by Transcranial Pulsed Current Stimulation (tPCS)
Chandler Sours 1,2 , Gad Alon 3 , Steven Roys 1 , and Rao P. Gullapalli 1,4
1
Diagnostic Radiology and Nuclear Medicine,
University of Maryland School of Medicine, Baltimore,
Maryland, United States,
2
Magnetic
Resonance Research Center (MRRC), Baltimore, Maryland,
United States,
3
Physical
Therapy and Rehabilitation Science, University of
Maryland School of Medicine, Maryland, United States,
4
Magnetic
Resonance Research Center (MRRC), Maryland, United
States
The effects of transcranial pulsed current stimulation (tPCS)
on resting state functional connectivity (rs-FC) within
the motor network were investigated. Four fMRI scans
were acquired, one motor paradigm and three (PRESTIM,
during STIM, POST-STIM) resting state fMRI scans. We
demonstrated changes in connectivity patterns that are
specific to tPCS including increased thalamo-cortical
connectivity during STIM and reduced cerebellar-cortical
involvement POST-STM. ROI analysis confirms reduced
strength and diversity of the motor network during STIM,
and reduced diversity POST-STIM. Our data confirm
previous findings using tDCS and strengthen the evidence
for the unique neuro-modulatory effects of tPCS.
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