Meeting Banner
Abstract #4192

Modulation of Resting State Functional Connectivity of the Motor Network by Transcranial Pulsed Current Stimulation (tPCS)

Chandler Sours 1,2 , Gad Alon 3 , Steven Roys 1 , and Rao P. Gullapalli 1,4

1 Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States, 2 Magnetic Resonance Research Center (MRRC), Baltimore, Maryland, United States, 3 Physical Therapy and Rehabilitation Science, University of Maryland School of Medicine, Maryland, United States, 4 Magnetic Resonance Research Center (MRRC), Maryland, United States

The effects of transcranial pulsed current stimulation (tPCS) on resting state functional connectivity (rs-FC) within the motor network were investigated. Four fMRI scans were acquired, one motor paradigm and three (PRESTIM, during STIM, POST-STIM) resting state fMRI scans. We demonstrated changes in connectivity patterns that are specific to tPCS including increased thalamo-cortical connectivity during STIM and reduced cerebellar-cortical involvement POST-STM. ROI analysis confirms reduced strength and diversity of the motor network during STIM, and reduced diversity POST-STIM. Our data confirm previous findings using tDCS and strengthen the evidence for the unique neuro-modulatory effects of tPCS.

This abstract and the presentation materials are available to members only; a login is required.

Join Here