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Abstract #4141

Estimating Test-Retest Reliability in Functional MR Imaging: three-state independence model

Yue Zhang 1 , Xiaoying Wang 2 , Jue Zhang 1 , Xiaoping Hu 3 , and Jing Fang 1

1 College of Engineering, Peking University, Beijing, Beijing, China, 2 Department of Radiology, Peking University First Hospital, Beijing, Beijing, China, 3 Department of Biomedical Engineering, Georgia Institute of Technology / Emory University, Atlanta, Georgia, United States

The reliability is important for functional magnetic resonance imaging (fMRI) data. Previous study has developed a statistical model (independence model) to quantify the test-retest reliability with only two states (active or inactive). More and more fMRI experiments have detected three state regions in the brain, including active, deactive and non-significant regions. In order to quantify the test-retest reliability of the fMRI data with three state regions, this study developed the three-state independence model. The model was applied to acupuncture fMRI data, the results indicated that the reliability of BOLD was higher than that of CBF.

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