Abstract #4069
Cognitive effects of breast cancer therapies: univariate and multivariate analyses of brain connectivity
Scott James Peltier 1 , Marc Berman 2 , Mary Kathleen Askren 3 , Bratislav Misic 4 , Mi Sook Jung 1 , Anthony Randal McIntosh 4 , Lynn Ossher 1 , Min Zhang 1 , Patricia Reuter-Lorenz 1 , and Bernadine Cimprich 1
1
University of Michigan, Ann Arbor, MI,
United States,
2
University
of South Carolina, SC, United States,
3
University
of Washington, WA, United States,
4
University
of Toronto, Ontario, Canada
This study investigates resting-state network
correlations in women treated for breast cancer and
age-matched healthy controls. In addition, a
partial-least squares analysis was performed. Univariate
and multivariate analyses both exhibited differential
patterns of connectivity across groups and time. This
may form the basis for improved diagnostic and
monitoring techniques for cognitive changes associated
with breast cancer and its treatment.
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