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Abstract #4023

Age-associated Changes in Triceps Surae Muscle Composition and Plantarflexor Strength an MR imaging based Study with Ultra-short Echo-time (UTE) and Fat-Water Quantification of Connective, Adipose and Contractile Tissues.

Robert Csapo 1 , Vadim Malis 2 , Usha Sinha 3 , Jiang Du 4 , and Shantanu Sinha 1

1 Radiology, University of California at San Diego, San Diego, CA, United States, 2 Physics, San Diego State University, San Diego, CA, United States, 3 Physics, San Diego State University, CA, United States, 4 Radiology, University of California at San Diego, CA, United States

Aging skeletal muscles are characterized by a progressing accumulation of intramuscular, non-contractile tissues. To quantitate the amount of intramuscular adipose (IMAT) and connective (IMCT) tissues, MR-based fater-water quantitation (IMAT) and ultrashort echo time (IMCT) imaging techniques were applied to the study of the Triceps Surae complex in young (YW) and senior (SW) women. Both IMAT and IMCT contents were significantly larger in SW. Additional measurements of plantarflexor strength and Triceps Surae volumes suggest that the inclusion of non-contractile tissues is likely to negatively affect a muscles intrinsic capacity to generate force at older age.

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