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Abstract #3938

MYOCARDIAL PERFUSION IMAGING USING TRANSIENT-PHASE SPIRAL-IN/OUT SSFP

Xue Feng 1 , Yang Yang 1 , David Lopez 2 , Michael Salerno 2,3 , and Craig H Meyer 1,3

1 Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 2 Medicine, University of Virginia, Charlottesville, VA, United States, 3 Radiology, University of Virginia, Charlottesville, VA, United States

Myocardial first-pass perfusion imaging is a promising diagnostic tool for the assessment of ischemic heart disease. Most studies utilize a saturation recovery (SR) preparation for T1 weighting and a spoiled GRE readout module. Spiral imaging, due to its high acquisition speed and robustness against motion artifacts, has been successfully adopted in this application combined with the SR GRE sequence using the traditional spiral-out trajectory. SR combined with a transient SSFP readout is an alternative sequence that can provide higher SNR. The spiral-in/out bSSFP sequence is advantageous over the traditional spiral-out bSSFP sequence since it can take advantage of the refocusing mechanism at TE = TR/2 to increase SNR and automatically achieve first gradient moment nulling due to the symmetry. In this study we will combine the spiral-in/out trajectory with the SR SSFP sequence and acquire perfusion data in the transient phase.

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